Biostimulatory fillers (collagen stimulators) have a different effect from hyaluronic ones. In addition to filling skin wrinkles, those fillers stimulate the synthesis of collagen by the body, ensuring lasting results. Collagen is one of the most important structural proteins and is responsible for skin strength and elasticity. Over time, skin gradually loses its natural collagen, resulting in the appearance of the first signs of ageing – wrinkles, loss of elasticity and unattractive sagging. As a result of the application of collagen stimulators, new and more resistant connective tissue is generated in the subcutaneous layers, making skin tighter, thicker and healthier.

The biostimulatory filler whose efficacy we can guarantee is Ellanse.

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Biostimulatory fillers are an innovative technology, guaranteeing an excellent safety profile and a lasting effect. Active stimulators are used to produce new type I collagen and are applied both to sculpt the face and to add volume and an elegant contour. Collagen stimulators are suitable for skin tightening, lifting and rejuvenation and for filling deep lines and wrinkles in certain areas: nasolabial, chin, cheekbones, cheeks and nose, as well for revitalising hand skin. An important feature is the possibility to choose the lastability (resorption period) of the biostimulatory filler, with the range on offer including products that last 1 to 4 years.

Ellanse Is an innovative biostimulatory dermal filler with a lasting effect, representing a revolution in contour plastics, with its ability to create a foundation that supports the structure of the face. The filler contains an aqueous gel vehicle (carboxymethyl cellulose) and an active substance (polycaprolactone) that stimulates the synthesis of new collagen.






  • Injectable treatment

Recovery period

  • It produces visible results immediately after the procedure but the final effect resulting from collagen generation by the body starts to be visible around 30 days after insertion and continues to intensify for 3-4 months. Avoid intense sun exposure, saunas, steam rooms, sports and machine-assisted procedures.


  • Pregnancy
  • Breastfeeding
  • Infectious diseases
  • Viral and bacterial skin infections
  • Oncological diseases


Biostimulatory fillers are a natural substance in the human body and stimulate the synthesis of new collagen. No special preparations are necessary before the procedure. Clean skin is all that is required. The treatment areas are determined in advance at Dermatological examinations and consultations. Anaesthesia is administered prior to the injectable procedure to ensure even patients with a low pain threshold are comfortable. A carefully measured amount of biostimulatory filler is injected during the procedure.

Frequently asked questions:

The dermatologist determines where the filler should be inserted, taking into account the patient’s anatomical features. The procedure lasts around 20-30 minutes.

The filler is spread evenly in the cheekbone area, with the results visible immediately.

No recovery period is required for this procedure. Redness or swelling may appear at the injection site, but the discomfort passes quickly (a few hours to a few days).

The effect is visible immediately and lasts around a year.

The procedure can be repeated again after the filler’s full or partial degradation.

  • Hypersensitivity to various types of fillers;
  • Skin injury at the injection site.